INSEMA

Study Information

PI: Toralf Reimer
Study supported by EUBREAST
Trial design: prospective randomised trial with focus to de-escalation of axillary surgery in the adjuvant setting
Primary outcome: 5-year invasive disease-free survival (SLNB versus no SLNB in breast-conserving surgery) Key secondary outcome: 5-year invasive disease-free survival (SLNB alone versus completion ALND in pN1a(sn) cases)

Axillary Surgery in Breast Cancer — Primary Results of the INSEMA Trial – New England Journal of Medicine

Reimer, Toralf, SABCS, December 2025 (Secondary Outcomes)

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