Project Summary
- Study initiated by EUBREAST e.V.
- Trial design: Investigator-initiated non-interventional observational international prospective / retrospective
cohort study to evaluate risk factors, clinical courses and therapeutic strategies in patients with granulomatous mastitis - Primary outcomes:
- Duration of symptoms depending on treatment strategy
- Proportion of patients presenting with specific symptoms (e.g., pain, redness,
palpable mass)
- Secondary outcomes:
- Type and duration of systemic treatment
- Number of surgeries, if performed
- Recurrence rate
- Risk factors associated with recurrence
- Time between first symptoms occurring and first histological confirmation
- Presentation on breast imaging (mammography, sonography, MRI, if performed)
- For more information, please contact gramareg@eubreast.org
*Please note that there is sensitive content (medical images) found in the Study Protocol and Initiation Videos.
Principal Investigators
| Prof. Dr. med. Maggie Banys-Paluchowski Vice-Chair of EUBREAST e.V. Head of Breast Cancer Center Head of Center for Familial Breast and Ovarian Cancer Department of Gynecology and Obstetrics University Hospital Schleswig-Holstein, Campus Lübeck Lübeck, Germany |
| Priv.-Doz. Dr. med. Natalia Krawczyk Leading Senior Physician Department of Gynecology and Obstetrics University Hospital Düsseldorf Düsseldorf, Germany |
Steering Board
| Dr. Sadaf Alipour Professor of Oncologic Surgery Breast Surgeon- Arash Women’s Hospital Deputy of Research- Breast Disease Research Center Tehran University of Medical Sciences Tehran, Iran |
| Prof. Dr. med. Vesna Bjelic-Radisic Head of the Breast Center and the Department of Senology Helios University Hospital Wuppertal Wuppertal, Germany |
| Prof. Dr. Jana de Boniface Associate Professor at the Department of Molecular Medicine and Surgery Karolinska Institutet Department of Surgery, Breast Centre Capio St. Göran’s Hospital Stockholm, Sweden |
| Prof. Dr. med. Nina Ditsch Treasurer of EUBREAST e.V. Head of Breast Cancer Center University Hospital Augsburg Augsburg, Germany |
| Prof. Maria Luisa Gasparri Treasurer of EUBREAST ETS Department of Gynecology and Obstetrics Ospedale Regionale di Lugano EOC Centro di Senologia della Svizzera Italiana (CSSI),Ente Ospedaliero Cantonale Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI) Lugano, Switzerland |
| Prof. Oreste Gentilini Chairman of EUBREAST ETS Vita-Salute San Raffaele University Head of Breast Surgery San Raffaele Scientific Institute Milan, Italy |
| Prof. Dr. med. Markus Hahn President of German Society of Ultrasound in Medicine (DEGUM) Head of Experimental Senology Department of Women’s Health University Hospital Tübingen Eberhard Karls University of Tübingen Tübingen, Germany |
| Priv.-Doz. Dr. med. Steffi Hartmann Leading Senior Physician Department of Gynecology and Obstetrics University Hospital Rostock Rostock, Germany |
| Prof. Dr. med. Güldeniz Karadeniz Çakmak Professor of Surgery Director of Breast and Endocrine Unit Zonguldak BEUN The School of Medicine Kozlu/Zonguldak, Turkey |
| Prof. Cliona Kirwan Professor of Surgery Clinician Scientist in Surgical Oncology and Consultant Oncoplastic Breast Surgeon Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester Manchester, United Kingdom |
| Prof. Dr. med. Thorsten Kühn Chairman of EUBREAST e.V. Department of Gynecology and Obstetrics University of Ulm Ulm, Germany |
| Dr. Yazan Masannat Consultant Oncoplastic Breast Surgeon Broomfield Hospital, Mid & South Essex NHS Trust, Chelmsford, Essex, England, UK Visiting Associate Professor Anglia Ruskin University, Cambridge, England, United Kingdom |
| Dr. Rosa Di Micco Vice-Chair of EUBREAST ETS Breast Surgery Unit San Raffaele Scientific Institute Milan, Italy |
| Prof. Dr. med. Annette Lebeau Senior physician Institute of Pathology University Medical Center Hamburg-Eppendorf | UKE Hamburg, Germany Group Praxis for Pathology Lübeck, Germany |
GraMaReg Study Protocol and other documents for download
Feasibility Questionnaire
Feasibility Questionnaire (in English)
